* indicates co-first authorship 2023 26. Trumble B.C., Negrey J., Koebele S.V., Thompson R.C., Wann L.S., Allam, A.H., Beheim B., Sutherland L., Sutherland J.D., Eid Rodriguez D., Michalik D.E., Rowan C.J., Lombardi G.P., Garcia A.R., Cummings D.K., Seabright E., Alami S., Kraft T.S., Hooper P., Buetow K., Irimia A., Gatz M., Finch C.E., Stieglitz J., Gurven M.D., Kaplan H., Thomas G.S., HORUS and THLHP Teams. Testosterone is positively associated with coronary artery calcium in a low cardiovascular disease risk population. 2023. Evolution, Medicine, and Public Health. 16;11(1):472-484. doi: 10.1093/emph/eoad039. eCollection 2023. PMID: 38145005
25. Koebele, S.V., Bernaud, V.E., Northup-Smith, S.N., Willeman, M.N., Strouse, I.M., Bulen, H.L., Schrier, A.R., Newbern, J.M., DeNardo, D.F., Mayer, L.P., Dyer, C.A., Bimonte-Nelson, H.A. Gynecological surgery in adulthood imparts cognitive and brain changes in rats: a focus on hysterectomy at short, moderate, and long-term intervals after surgery. 2023. Hormones and Behavior. 155: 105411. doi: 10.1016/j.yhbeh.2023.105411. PMID: 37659358.
24. Trumble, B.C., Charifson, M., Kraft, T., Garcia, A.R., Cummings, D.K., Hooper, P., Lea, A.J., Eid Rodriguez, D., Koebele, S.V., Buetow, K., Beheim, B., Minocher, R., Gutierrez, M., Thomas, G.S., Gatz, M., Stieglitz, J., Finch, C.E., Kaplan, H., Gurven, M. Apolipoprotein-ε4 is associated with higher reproductive fecundity in a natural fertility population. 2023. Science Advances. 9(32):eade9797. doi: 10.1126/sciadv.ade9797. PMID: 37556539.
23. Bernaud, V.E., Koebele, S.V., Northup-Smith, S.N., Willeman, M.N., Barker, C., Schatzki-Lumpkin, A., Valenzuela Sanchez, M., Bimonte-Nelson, H.A. Evaluations of memory, anxiety, and the growth factor IGF-1R after post-surgical menopause treatment with a highly selective progestin. Behavioural Brain Research. 448:114442. doi: 10.1016/j.bbr.2023.114442. PMID: 37085118.
2022 22. Bernaud, V.E., Bulen, H.L., Peña, V.L., Koebele, S.V., Northup-Smith, S.N., Manzo, A.A., Valenzuela Sanchez, M., Opachich, Z., Ruhland, A.M., Bimonte-Nelson, H.A. Task-dependent learning and memory deficits in the TgF344-AD rat model of Alzheimer’s disease: Three key timepoints through middle-age in females. Scientific Reports. 12(1):14596. doi: 10.1038/s41598-022-18415-1. PMID: 36028737.
21.Koebele, S.V., Ycaza Herrera, A., Taylor, C.M., Barth, C., Schwarz, J.M. 2022. Editorial: Sex Hormone Fluctuations Across the Female Lifespan: Mechanisms of Action on Brain Structure, Function, and Behavior. Frontiers in Behavioral Neuroscience: Behavioral Endocrinology. 16:964740. doi: 10.3389/fnbeh.2022.964740. PMID: 35874649Open Access Link.
20. Koebele, S.V., Poisson, M.L., Palmer, J.M., Berns-Leone, C., Northup-Smith, S.N., Peña, V.L., Strouse, I.M., Bulen, H.L., Patel, S., Croft, C. Bimonte-Nelson, H.A. 2022. Evaluating the Cognitive Impacts of Drospirenone, a Spironolactone-Derived Progestin, Independently and in Combination with Ethinyl Estradiol in Ovariectomized Adult Rats. Frontiers in Neuroscience (Neuroendocrine Science). 16:885321. doi: 10.3389/fnins.2022.855321. PMID: 35692432. Open Access Link.
2021 19. Zeibich, L.*, Koebele, S.V. *, Bernaud, V.E., Ilhan, Z.E., Dirks, B., Northup-Smith, S.N., Neeley, R., Maldonado, J., Nirmalkar, K., Files, J.A., Mayer, A.P., Bimonte-Nelson, H.A., Krajmalnik-Brown, R. 2021. Surgical Menopause and Estrogen Therapy Modulate the Gut Microbiota, Obesity Markers, and Spatial Memory in Rats. Frontiers in Cellular and Infection Microbiology: Microbiome in Health and Disease. September: Volume 11, Article 702628. doi: 10.3389/fcimb.2021.702628. PMID: 34660336. Open Access Link.
18. Koebele, S.V., Hiroi, R., Plumley, Z.M.T., Melikian, R., Prakapenka, A.V., Patel, S., Carson, C., Kirby, D., Mennenga, S.E., Mayer, L.P., Dyer, C.A., Bimonte-Nelson, H.A. 2021. Clinically-Used Hormone Formulations Differentially Impact Memory, Anxiety-Like, and Depressive-Like Behaviors in a Rat Model of Transitional Menopause. Frontiers in Behavioral Neuroscience: Behavioral Neuroendocrinology. July: Volume 15, Article 696838. doi: 10.3389/fnbeh.2021.696838. PMID: 34366807. Open Access Link.
17. Koebele, S.V., Quihuis, A.M., Lavery, C.N., Plumley, Z.M.T., Casteneda, A.J., Bimonte-Nelson, H.A. 2021. Estrogen Therapy Modulates the Impact of Cognitive Experience and Task Complexity on Memory in Middle-Aged Surgically Menopausal Rats. 2021. Journal of Neuroendocrinology. June: 33(9): e13002. doi: 10.1111/jne.13002. PMID: 34378820.
11. Koebele, S.V. and Bimonte-Nelson, H.A. 2019. “Response to Letter to the Editor: ‘Hysterectomy Uniquely Impacts Spatial Memory in a Rat Model: A Role for the Nonpregnant Uterus in Cognitive Processes’.” Endocrinology, 160(2): 461-462. doi: 10.1210/en.2019-00004. PMID: 30649267. PMCID: PMC7295935.
10. Koebele, S.V., Palmer, J.M., Hadder, B., Melikian, R., Fox, C., Strouse, I.M., DeNardo, D.F, George, C., Daunis, E., Nimer, A., Mayer, L.P., Dyer, C.A., Bimonte-Nelson, H.A. 2019. Hysterectomy uniquely impacts spatial memory in a rat model: A role for the non-pregnant uterus in cognitive processes. Endocrinology, 160(1):1-19. doi: 10.1210/en.2018-00709. PMID: 30535329. PMCID: PMC6293088.
9.Holter, M.C., Hewitt, L.T., Koebele, S.V., Judd, J.M., Xing, L., Bimonte-Nelson, H.A., Conrad, C.D., Araki, T., Neel, B.G., Snider, W.D., Newbern, J.M. 2019. The Noonan Syndrome-linked Raf1L613V mutation drives increased glial number in the mouse cortex and enhanced learning. PLOS Genetics. 15(4): e1008108. doi: 10.1371/journal.pgen.1008108. PMID: 31017896. PMCID: PMC6502435.
2017 8. Koebele, S.V., Mennenga, S.E., Hiroi, R., Quihuis, A.M., Hewitt, L.T., Poisson, M.L., George, C., Mayer, L.P., Dyer, C.A., Aiken, L.S., Demers, L.M., Carson, C., Bimonte-Nelson, H.A. 2017. Cognitive changes across the menopause transition: A longitudinal evaluation of the impact of age and ovarian status on spatial memory. Hormones and Behavior, 87: 96-114. doi: 10.1016/j.yhbeh.2016.10.010. PMID: 27793768. PMCID: PMC5479707.
7. Koebele, S.V. & Bimonte-Nelson, H.A. 2017. The endocrine-brain-aging triad where many paths meet: female reproductive hormone changes at midlife and their influence on circuits important for learning and memory. Experimental Gerontology (Special Issue: Neurobiology of Aging), 9:14-23. doi: 10.1016/j.exger.2016.12.011. PMID: 27979770. PMCID: PMC5479709.
2016 6. Koebele, S.V. & Bimonte-Nelson, H.A. 2016. Modeling menopause: The utility of rodents in translational behavioral endocrinology research. Maturitas. 87: pp. 5-17. doi: 10.1016/j.maturitas.2016.01.015. PMID: 27013283. PMCID: PMC4829404.
5. Hiroi, R., Weyrich, G., Koebele, S.V., Mennenga, S.E., Talboom, J.S., Hewitt, L.T., Lavery, C.N., Mendoza, P., Jordan, A., Bimonte-Nelson, H.A. 2016. Benefits of hormone therapy estrogens depend on the type of estrogen: 17β-estradiol and conjugated equine estrogens have differential effects on cognitive, anxiety-like, and depressive-like behaviors and increase tryptophan hydroxylase-2 mRNA levels in distinct subregions of the dorsal raphe nucleus. Frontiers in Neuroscience: Neuroendocrine Science. 10:517. doi: 10.3389/fnins.2016.00517. PMID: 28008302. PMCID: PMC5143618. Open Access Link.
2015 4. Koebele, S.V. & Bimonte-Nelson, H.A. 2015. Trajectories and phenotypes with estrogen exposures across the lifespan: What does Goldilocks have to do with it? Hormones and Behavior (Special Issue: Estradiol and cognition: molecules to mind). Vol. 74: pp. 86-104. doi: 10.1016/j.yhbeh.2015.06.009. PMID: 26122297. PMCID: PMC4829405.
3. Mennenga, S.E., Gerson, J.E., Kingston, M.L., Koebele, S.V., Tsang, C.W.S., Engler-Chiurazzi, E.B., Baxter, L.C., & Bimonte-Nelson, H.A. 2015. Understanding the cognitive impact of the contraceptive estrogen Ethinyl Estradiol: Tonic and cyclic administration impairs memory, and performance correlates with basal forebrain cholinergic system integrity. Psychoneuroendocrinology, 54: 1-13. doi: 10.1016/j.psyneuen.2015.01.002. PMID: 25679306. PMCID: PMC4433884.
2. Mennenga, S.E., Koebele, S.V., Mousa, A.A., Alderete, T.J., Tsang, C.W.S., Acosta, J.I., Camp, B.W., Demers, L.M., and Bimonte-Nelson, H.A. 2015. Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats. Steroids. SI: Measuring Estrogen Exposure and Metabolism, 99 (Pt A):16-25. doi: 10.1016/j.steroids.2014.08.010. PMID: 25249951. PMCID: PMC4398574.
2014 1. Mennenga, S.E., Baxter, L.C., Grunfeld, I.S., Brewer, G.A., Aiken, L.S., Engler-Chiurazzi, E.B., Camp, B.W., Acosta, J.I., Braden, B.B., Schaefer, K.R., Gerson, J.E., Lavery, C.N., Tsang, C.W.S., Hewitt, L.T., Kingston, M.L., Koebele, S.V., Patten, K.J., Ball, H., McBeath, M.K., and Bimonte-Nelson, H.A. 2014. Navigating to new frontiers in behavioral neuroscience: Traditional neuropsychological tests predict human performance on a rodent-inspired radial-arm maze. Front. Behav. Neurosci. 8:294. doi: 10.3389/fnbeh.2014.00294. PMID: 25159107. PMCID: PMC4158810. Open Access Link.
Book Chapter: 1. Bimonte-Nelson, H.A., Daniel, J.M., and Koebele, S.V. 2015. “The Mazes”. The Maze Book: Theories, Practice, and Protocols for Testing Rodent Cognition. Ed: Heather A. Bimonte-Nelson. Neuromethods, Vol. 94. XVIII, Springer Publishing, Humana Press.